Some think that thought is something that is indescribable, that it exists outside of the brain. That it is not able to be defined or that we have no way of understanding it. And to that line of reasoning, that it is only of metaphysical significance and cannot be compared with real matter or values.
I however consider that the mind solely exists in the brain and it is made up of the same matter as everything else. The only thing that differs is the structure and organization of that matter, which gives us consciousness and allows us to think and question the very nature of our own consciousness.
Science has allowed us to dissect the brain and discover its subcomponents. The brain is made of neurons in which some way of firing allows conscious thought. If those components are further sub-divided then there are molecules, then ions and atoms which allow electrical potentials. Humans have been able to further subdivide these atoms into smaller particles. These particles when arranged differently can be called other objects and have other functions. With this line of reasoning the brain is essentially an electronic device using living neurons instead of other matter usually made up of silicon, copper, gold, etc.
Once the structure and function is known on an atomic level, a model and theory of thought can be made that can be held up to experiments.